Centre for Integrated Systems Biology of Ageing & Nutrition

Newcastle University Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom

The Centre for Integrated Systems Biology of Ageing & Nutrition is a multidisciplinary research centre within Newcastle University. CISBAN's aim is to advance understanding of the complex mechanisms underpinning the ageing process and of how these are affected by nutrition, through the field of research known as systems biology. Systems biology is a new way of tackling complex biological problems. It uses a combination of the latest techniques for highly detailed measurements of cells and molecules, combined with sophisticated computing and mathematical modelling, to help us build up a complete picture of how the body's systems work.

Led by Professor Tom Kirkwood, CISBAN is an interdisciplinary centre combining talents of biologists, statisticians, mathematicians, computer scientists and engineers. Its purpose is to apply a systems approach to the biology of ageing and nutrition. Not only does this include a strong experimental biology component, there is also a large in silico research group comprised of modellers, statisticians, computational systems biologists. The wet lab experiments are led by Professor David Lydall (functional genomics and proteomics) and Professor Thomas von Zglinicki (integration of partial systems). The in silico team is led by Professor Anil Wipat.

Research Topics Currently Explored at the CISBAN

  • Cell senescence
  • Computational modelling
  • Dietary restriction
  • High-throughput techniques
  • Yeast genetics

Contact for outreach:

Darren Wilkinson, PhD

Telephone: +44 (0)191 222 7320

Ongoing international exchange:

[Pending information]

Funding opportunities:

[Pending information]

Relevant degree-granting programs:

[Pending information]