Manchester Centre for Integrative Systems Biology
University of Manchester, United Kingdom
The Manchester Centre for Integrative Systems Biology (MCISB) at the University of Manchester has been awarded £6.4M by the BBSRC and EPSRC to pioneer the development of new experimental and computational technologies in Systems Biology, and their exploitation. The MCISB is intended to provide a hub for cutting-edge systems biology research in the Manchester area, acting as a focal point for the creation of the necessary ideas and infrastructure, and for establishing new methods and routines.
The main goal of the MCISB is to bring together the technologies and skills necessary for the development of quantitative Systems Biology. These technologies and skills encompass a wide range of experimental (Molecular Biology / Biochemistry / Biophysics), mathematical and computational (Modelling / Data Integration / Text Mining etc.) activities. While the methods developed are intended to be generic, we seek to demonstrate their utility with a real system. To this end, the initial focus of research is on the baker's yeast (Saccharomyces cerevisiae), which is an ideal organism in which to explore techniques for the development of integrated models of important cellular systems, because the organism is highly amenable to genetic manipulations and to high-throughput technologies.
Research Topics Currently Explored at the MCISB
- Bio-molecular interaction
- Data analysis, data standards and databases
- Mathematical modeling of biological processes
- Metabolomics
- Microbiology
- Molecular biology
- Protein purification
- Proteomics
Contact for international outreach:
pending...
Ongoing international exchange:
pending...
Relevant quantitative and systems biology degree programs:
The Doctoral Training Centre Integrative Systems Biology at the University of Manchester trains students for a PhD in Systems Biology. It is one of three UK Systems Biology training centres funded by the British research councils EPSRC and BBSRC.