San Diego Center for Systems Biology
University of California, San Diego, California
The San Diego Consortium for Systems Biology was founded in 2005 to promote collaborative research and interdisciplinary research training in Systems Biology on the Torrey Pines mesa and beyond. In 2010, SDCSB became an NIGMS Center for Systems Biology, to promote and safeguard the transitioning biomedical research from a phenomenon/data-driven science to a quantitative, math-based science. Now known as the San Diego Center for Systems Biology, SDCSB comprises activities in (i) scientific research, (ii) scientific outreach, and (iii) educational outreach.
SDCSB supports investigator-driven research projects and research cores. The three research cores address conceptual, technological, and educational challenges, and cover three specific areas that are critical to the mission of the Center: Network Bioinformatics, Mathematical Modeling and Cellular Dynamics. The investigator-driven research projects are organized into four programs that address innate immune, inflammatory, and genotoxic responses, as well as design principles of dynamic control. A Seed Grant Program identifies promising projects for investigator cycling, thus broadening the impact of the Center’s research activities.
Research Topics Currently Explored at the SDCSB
- Cellular dynamics
- Developmental genetic network stability
- Immune cell stress response
- Mathematical modeling
- Network bioinformatics
- RNA interference
- Transcriptional analysis
Contact for outreach:
Cookie Santamaria
Executive Assistant for the SDCSB
Phone: (858) 534-1981
Ongoing international exchange:
[Pending information]
Funding opportunities:
Within the San Diego area: SDCSB will offer one-year $25,000 seed grants to investigators who would like to explore the utility of this approach for addressing their own research questions. If the initial project proves to be promising, the investigators could then become full-fledged members of the center. The 2010/2011 seed grant recipients are listed here.
Relevant degree-granting programs:
SDCSB synergizes with the UCSD PhD Program in Bioinformatics and Systems Biology and catalyzes the transformation of undergraduate and graduate curricula in biological, biomedical, and biochemical sciences at UCSD to include bioinformatic network analysis and mathematical modeling approaches.